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Transcription Factors
Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
Systematic comparison of transcription factor isoforms revealing widespread divergence in DNA binding, protein interactions, and regulatory activity, often linked to intrinsically disordered regions and misregulated in tumors.
Lambourne L
,
Mattioli K
,
Santoso C
,
Sheynkman G
,
Inukai S
,
Kaundal B
,
Berenson A
,
Spirohn-Fitzgerald K
,
Bhattacharjee A
,
Rothman E
,
Shrestha S
,
Laval F
,
Carroll BS
,
Plassmeyer SP
,
Emenecker RJ
,
Yang Z
,
Bisht D
,
Sewell JA
,
Li G
,
Prasad A
,
Phanor S
,
Lane R
,
Moyer DC
,
Hunt T
,
Balcha D
,
Gebbia M
,
Twizere J
,
Hao T
,
Holehouse AS
,
Frankish A
,
Riback JA
,
Salomonis N
,
Calderwood MA
,
Hill DE
,
Sahni N
,
Vidal M
,
Bulyk ML
,
Fuxman Bass JI
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