Isoforms

Beyond the gene: Decoding alternative isoforms
An invited review on how alternative isoforms expand the functional output of the genome and why they matter in disease.
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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
Systematic comparison of transcription factor isoforms revealing widespread divergence in DNA binding, protein interactions, and regulatory activity, often linked to intrinsically disordered regions and misregulated in tumors.
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